Strong side effects for months after low amounts of hydroxoB12 and R5P. Can anyone help me?
So I’m homozygous for A66G MTRR and heterozygous for A2756G MTR and A664A MTR and C677T. My homocysteine level was about 15.8. For 3 months I took 125 mcg hydroxoB12 once a week and the side effects were ok. Then at the the 8 mg R5P, activated riboflavin. After the riboflavin I began to feel exhausted, extremely weak and sore, my eyes watered for weeks, and my urine foamed. My blood pressure shot up. Homocysteine dropped to 8. The symptoms slowly began to go away over weeks. If I take blood pressure medicine, they become stronger. So some symptoms are still here 8 weeks in.
Does anyone have an idea what’s going on or what has helped?
Posted Jun 15, 2026, 12:56 PM UTC
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