r/ibs•
Thatweasel

Something like loperamide but milder?

Question

So I've suffered for chronic, non watery diarrhoea with poorly formed stool for a long, long time. I've discovered loperamide helps a lot pretty much instantly but often pushes the needle too far in the other direction, not quite to the point of what I'd consider constipation but enough to cause me to strain

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Are there any medications that work similarly but are just a little bit less aggressive in how much they slow motility? Has anyone had a similar experience and found something that reliably works?

Posted Jun 20, 2026, 11:53 PM UTC

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