Mixing Oxycodone with Tramadol
Has anyone here ever had a doctor prescribe an extended release Tramadol with Oxycodone? I've been in pain management since 2019. I've been prescribed Oxycodone 4x daily for around 4 years, but have now reached the point that it's not effectively managing my pain. When I told my doctor this, she suggested dropping down to Oxycodone 3x daily plus adding an extended release Tramadol 50-100mg to see if that will help. Has anyone ever tried this combination, and if so, how did it work for you?
Posted Jun 25, 2026, 5:00 PM UTC
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