Depression/SI

Negative Experience

Hi, new to this sub. I just started bupropion 100mg SR about a week ago. I’ve been taking lurasidone 20mg and lamotrigine 25mg for bipolar 2 and my provider prescribed the Wellbutrin to help with ADHD and general anxiety. I feel like the past 2 days, I’ve noticed myself being more irritable, but just chalked it up to stress. But today the depression is very noticeable and I’m having thoughts of self harm and suicidal ideation for the first time since I’ve started the other meds. I’m also picking fights with my partner and can tell that I’m being self sabotaging (which is unfortunately typical for me when I get down like this), and it’s just shitty. Not just for me. But for him. But I don’t know what to do. Is this a normal side effect in the beginning where it gets worse before it gets better or should I be concerned? Thank you in advance for your kindness and advice 🤍

Posted Jul 4, 2026, 6:23 PM UTC

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