Does anyone have toxic female friends?

I have this female friend that I have been genuinely confused about. Like I honestly don’t know she’s just being disrespectful on purpose or just couldn’t tell things were not funny to say.

We used to get along and I think I have been quite respectful and kept everything in boundaries. I recall helping her move while she showed little appreciation (if not impatience). And her words showing outright contempt for me or my belongings.

I feel like sometimes I’m not really sensitive to friends being rude to me. I have always preferred female friends growing up. But this girl is really making me think if certain women just regard gay men as funny little punchbags .