Some references on the WASF3 connection

https://www.pnas.org/doi/10.1073/pnas.2302738120

https://wms-site.com/press-media/1175-decoding-chronic-fatigue-the-crucial-role-of-wasf3-in-mitochondrial-dysfunction-in-me-cfs

https://www.psychiatrist.com/news/a-protein-that-zaps-cellular-energy-may-underlie-chronic-fatigue

https://www.healthrising.org/blog/2023/08/16/nih-mitochondria-chronic-fatigue-syndrome/

https://meassociation.org.uk/2023/08/research-a-protein-that-disrupts-a-cells-energy-structure-may-be-a-culprit-in-me-cfs-long-covid/

https://ui.adsabs.harvard.edu/abs/2023PNAS..12002738W/abstract

https://www.science.org/content/article/protein-disrupts-cells-energy-centers-may-be-culprit-chronic-fatigue-syndrome?__cf_chl_f_tk=LhTouoLi45u0XkS1pxDee2_BKQ772aKpejyUN54zvbQ-1783343645-1.0.1.1-rI9HTQjNa0y.D4I68BAvrCc2ZY.mwxPKWBDWdrLy0gQ

WASF3 is a protein produced in the Endoplasmic Reticulum due to ER Stress, which can be from heavy oxidation, viral overload, and many other issues. Heavy oxidation can have many different root causes and can also directly damage mitochondria.

THE WASF3 causes a break in the mitochondria supercomplex