Where to put estradiol patch for best absorption?

I think my body is a bit tricky or wants to challenge me. I am having a hard time trying to find the best place to put the patch so it absorbs the best.

I tried patches a few months ago and then I decided to try Divigel which for me only made things worse. I would get a surge of the estrogen for a couple hours but then it would drop quickly so 2 months later, I went back to the patches.

Last week I decided to change the location of my patch from my right abdomen area to my right upper butt for better absorption. It worked fantastic. But on Sunday when I changed the patch and put it on my upper left butt, my symptoms started to return - back pain, joint paints, tired, no energy, moody, and just feeling miserable.

Anyone else have these issues and what did you do?