Could repeated use (of psychs) in a specific room cause altered perception of said room?

Like how addicts get cravings from rooms they abuse in, but instead would the room kinda look weird? like hppd but in a specific space.

I use pretty frequently and use my bedroom has my trip space and its made my room feel a little abnormal if that makes sense. (I know how long your suppose to wait between trips, and know about hppd, just wanna know if it can effect a specific space).