r/zoloft•
papapapapaya67

I am regretting starting sertraline

Vent

Basically I'm worried about my sex drive disappearing.

I have been on 25mg sertraline for 3 days now. The side effects have been fine for the most part, at worst they just feel like a bad day of depression which I've dealt with before: my issue comes with what *could* happen while on it.

Granted I maybe should've researched more before agreeing to taking these, however I feel as though my GP didn't go through the side effects enough too.

I've already noticed a decrease in sensation in that area which worries me, I don't want to develop PSSD, I have a partner that I would very much like to continue being intimate with. I also suffer from vaginismus (which I have been in the process of treating for over half a year) and while having intercourse isn't the main and only goal of relieving this, it is a big one, and I worry it will be for nothing if sertraline strips me of any sexual desire.

Even if I don't necessarily end up with something as severe as PSSD, my sex life is still somewhat impacted, which is infuriating. I don't want to sacrifice something so important just for a chance I could get better.

I have an appointment with a different GP next week where I will discuss my worries regarding this, but I just wanted to see what people who actually have taken this medicine have to say about it.

Posted Jul 10, 2026, 5:50 PM UTC

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