The Doctor has absorbed the Time Vortex itself on multiple occasions and was able to weaponise it. It can be accessed by looking into the Heart of the TARDIS as Rose Tyler did. With it, The Doctor’s durability also scales to the Time Vortex as it flowed through “Every nerve” and “Every molecule” of his body.

After jumping into the Time Vortex, the Doctor absorbed the Vortex Energy to become a transcendent being. While in this state, he was powerful enough to instantly disintegrate the Flood Cybermen from existence and essentially became a god that could see all of reality until he decided to give up his god-hood in order to save his companion.

In the Ninth Doctor’s Final Story “The Parting of the Ways”, in order to save Rose Tyler’s life, the Doctor absorbed Vortex Energy from her into himself and then released it back into the TARDIS. While in this state, he became an extremely powerful being, its consequence on his body was too much, and he regenerated into the Tenth Doctor.

After absorbing Vortex Energy from the Heart of the TARDIS, this Ninth/Tenth Doctor companion became the entity known as [Bad Wolf](https://tardis.fandom.com/wiki/Bad_Wolf_(entity)). Considering how we know the Doctor can absorb the energy of the TARDIS (at the cost of their own life eventually) and absorb energy from the Time Vortex, scaling the Doctor and their higher tier forms to Rose Tyler/Bad Wolf should be viable.

* Has been stated to be capable of destroying the entire universe ([I am a Dalek](https://tardis.fandom.com/wiki/I_Am_a_Dalek_(novel))).

The Fifteenth Doctor channeled his regeneration energy through the TARDIS console into the Time Vortex to rewrite reality.

Time Vortex Doctor