Mounjaro has helped me!

I’ve been dealing with worsening MCAS for years after years of trying to treat and heal from SIBO. I’ve tried many supplements and antihistamines with little to no effect. The only slight help was Pepcid.

The food triggers (salicylates and histamines) incredibly limited my diet, and I leaned on activated charcoal when I accidentally ingested a trigger food and started to react.

I had almost all of the MCAS symptoms except the lung related ones. I tried LDN, but my hyper sensitive body reacted poorly to any doses above 0.5mg. My doctor recommended staying at 0.5mg dose continuously just in case that helped.

As a last ditch attempt, my doctor recommended trying Mounjaro. I did a week of 0.25 mg, and by the second week of the same dose, I can have coffee every day with no reaction (when I used to have a several day reaction from one cup!!) I don’t even need to take three types of antihistamines every day! I am still taking NoPhenol and DAO with each meal just in case, but I’m going to try weaning off of those and reintroducing fruits, vegetables, and eventually spices 🥳

I’m still very early in this, and concerned this might cause my SIBO to return, but I just want to add a hopeful post that this has worked for me, and I hope others can feel this relief!

Posted Jul 10, 2026, 7:36 PM UTC · locked

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