Started standard dose of Tirz 2.5 mg -- Need some support and reassurance

Hi everyone,

I started microdosing Tirzepatide on July 5th with 2.5 mg. I’ve already lost about 25 lbs before this and had hit a plateau with really intense food obsession (especially pastries). Years of chronic stress + a surgery last year sent my cravings into overdrive. I couldn’t focus on anything else until I gave in.

I dosed right before my period (I’m already iron deficient), and the first week was absolutely horrendous — hypomanic/overstimulated feelings, anxiety, the works. But I pushed through and found a rhythm: small high-protein meals throughout the day (5x).
Now I’m feeling more or less normal most of the day. Blood sugar has never gone dangerously low (lowest in the 4s), but I’m autistic with high interoception so I over-analyze every sensation and it feels scary. Mornings are still the hardest — I wake up manic/panicky even though nothing is actually wrong. Driving still makes me anxious and I feel overstimulated.

Has anyone else had this experience with microdosing? Did the overstimulation and morning anxiety settle down with time? Any tips for the driving anxiety or just general reassurance would mean a lot right now.

Thanks ❤️

Posted Jul 13, 2026, 4:33 PM UTC

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