Bad side symptoms

Hi everyone,

I’m on day 7 of taking Zoloft (sertraline) for anxiety.
I started on 50 mg, but by day 4 I was experiencing quite a bit of nausea, and from day 1 I had diarrhea. After speaking with my doctor, he reduced my dose to 25 mg.

What I’m struggling with most is that my anxiety actually feels worse than it did before starting Zoloft. My 20-minute train ride to work has become incredibly difficult. I get sweaty palms, feel nauseous, and constantly worry that I’m going to throw up and embarrass myself.

Once I get to work, I also feel much more anxious around my coworkers and clients. I’m new to the job and still in my probation period, so that probably adds to it. I definitely had some anxiety before starting Zoloft, but it feels much more intense now.
I’m just wondering if this is a normal part of starting sertraline or if it could mean it’s not the right medication for me. Should I keep pushing through, or is this something I should be concerned about?
Also, are there any medications that doctors commonly prescribe to help get through the initial adjustment period while waiting for Zoloft to start working?

I’d really appreciate hearing from anyone who’s been through something similar or has any advice. Thanks!

Posted Jul 25, 2026, 11:40 PM UTC

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