38M – PI-RADS 3 (8 mm focus), PSA 1.9, density 0.11, strong family history – biopsy booked
Had my mpMRI results back yesterday and got a PI-RADS 3 due to an 8 mm focus in the left posterior peripheral zone at the apex. Because of this, my age, and my family history (grandfather, father and uncle all had prostate cancer), the consultant has booked a transperineal MRI-US fusion targeted biopsy.
Looking for experiences from others who had a PI-RADS 3 finding, especially with similar MRI features (no restricted diffusion / no enhancement) and modest PSA density. What did your biopsy show and how did things go afterwards?
The nitty gritty stuff:
The Numbers
- Initial PSA: 2.18
- Repeat PSA: 1.9
- Prostate volume: 18 cc
- PSA density: ≈ 0.11
Symptoms
Mild urinary symptoms for a couple of months, urgency (felt in the glans), occasional sensation of incomplete emptying, mostly good flow.
MRI (1.5T):
- 8 mm PI-RADS 3 focus in the left posterior peripheral zone at the apex
- Slightly reduced ADC but no convincing restricted diffusion
- No post contrast enhancement
- Capsule smooth and intact
- Patchy low T2 changes reported as age-related
Thanks to reading!
Posted Aug 5, 2026, 1:29 PM UTC