What actually lowers epigenetic age in humans?

A new systematic review analyzed 41 human intervention studies covering diet, exercise, supplements, medications, and experimental therapies.

The researchers compared their effects across next-generation epigenetic clocks, including the widely discussed DunedinPACE, which estimates the current pace of aging rather than age in years.

Some results were promising. Others were far less convincing than popular longevity claims suggest.

🔗 Full analysis