Long-term effects from surgery and radiation?

I have metastatic urothelial carcinoma with distant metastasis to my brain. This is extraordinarily rare disease progression so there is no real treatment protocol.

I’ve had 3 tumours in my brain identified and treated approximately 1 year apart. The first two were located between my right frontal and parietal lobes and were removed surgically then treated with radiation(November 2023, December 2024). The third was very small, located left temporal and was treated with gamma blade radiation (October 2025). My last MRI, 3 months ago, was clear (no tumours, swelling, necrosis). I have my next MRI later this week.

I am experiencing very low energy and stamina, moodiness bordering on bitchiness, headaches, jaw pain, lethargy. I have a bunch of other medical concerns that are being followed by various doctors. I am and do seek medical advice and treatment on the regular, but I’m curious about anecdotal information about how long craniotomy and radiation effects last.

What have you experienced? How long did you feel less than ideal? Aside from brain injury from tumour removal, what physical, mental or emotional effects have stayed with you? For how long?

My neurologist and radiation oncologist tend to say “everyone is different” and try to treat me symptomatically, but I’m becoming overwhelmed with all the meds, their side effects and juggling their timing and their relationship with each other. I’m worried about complaining of how I’m feeling and having them prescribe more meds that adds to what I’m already juggling.

Any help? Any wisdom?