If you meet someone who doesn't have any friends, or has some friends that you don't think are good for them but that's the only hiccup, can you work with that?

Like everything else about them you like a lot, it's just one of those two situations. Would either of those things be enough for you to say it wouldn't work out, or do you not really care too much? If you have already been in this situation, how did you handle it?