Audio stutter/crackling when playing intensive games

Noticed over the last few weeks when playing games such as Red Dead Redemption 2 or Spider-Man 2 my system will over time start gradually bugging out and having more audio issues.

This happens on both headset audio and when playing out of speakers I have attempted to remedy this with various fixes including: Ensuring audio enhancements are off, Changing audio format, ensuring there were no power plan settings that were causing issues or throttling performance, trying both realtek and windows generic audio drivers, clean installing NVIDIA drivers and even changing settings in my BIOS that could've led to pc performance being reduced or throttled including CPU C-states. However it has felt like shooting bullets into the dark a bit because i can not work out where this issue is stemming from.

Any ideas would be helpful! My specs are:

MB: Gigabyte B550 Aorus Elite AX V2 Rev 1.0 on BIOS version F20
CPU: AMD Ryzen 5 4500
GPU: Asus Geforce RTX 3060 12GB Phoenix
RAM: 2x 8GB Kingston Fury Beast DDR4 at 3200MHz
NVMe SSD: Samsung 980 500gb
SATA SSD: Kingston A400 960gb
HDD: Seagate Barracuda 1TB 7200RPM
Headset: Logitech G432 Wired USB Headset