Which SSRIs are more likely to cause PSSD?

A few years ago, I tried Lexapro for a few months and then later tried Prozac for a few months. I experienced sexual side effects and they stopped once I got off them.

I’m supposed to start 25 mg of Zoloft today and I’m worried about it potentially giving me PSSD. If I didn’t get PSSD from other SSRIs, is there still a risk of me getting it with Zoloft? Is Zoloft more likely to give PSSD than Lexapro or Prozac?

Posted Aug 13, 2026, 4:13 PM UTC

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