Glans dekeratinizing-urea cream or PDRN?

Does anyone have any experience using Urea moisturizer or PDRN serum on glans for dekeratinization? Was getting urea moisturizer (for calluses) and PDRN serum (derived from salmon sperm supposedly??) for wife and realized they’re both for deep moisturizing, not surface level. Naturally my brain automatically associated them with potential restoring effectiveness lol