CF dad, when is it worth switching to Alyftrek

My 9 year old is on Trykafta right now. He's got a relatively mild case, Del508 and RH117 7T, never been hospitalized.

He qualifies for Alyftrek, but hates needles and so doesn't want to switch medications because that would involve blood tests (quarterly, I think) for a year.

People who have switched, how much better is it? Is it worth disappointing a kid? What would you suggest is best for his health?