r/SIBO•
Chu-lal

How do you treat Gastritis when you have anti-vinculin antibodies?

Wassup guys, I was hoping to poke at your brains.

Sorry if the title of the post is a bit weird, but I'm still trying to figure out my situation. I got an endoscopy that confirmed I have gastritis and I got the IBS SMART test which came back positive for anti-vinculin. Also, my symptoms did start with a bout of food poisoning

However, it's not clear to me if bacteria have migrated up into my small intestine. The reason I say this is because I do not have a sensitivity to FODMAPs(rice, bread, potatoes and bananas are super friendly on my stomach), I don't have diarrhea or constipation (stool is normal), breath tests came back negative, and antibiotics/elemental diet and carnivore diet did nothing to relieve my symptoms.

My symptoms include stomach discomfort and really bad brainfog. Recent labwork shows that my iron and b-12 are deficient.

Is it possible to have anti-vinculin without having bacteria use the opportunity to move into the small intestine? Have you guys heard of such a thing before?

Anyways, the main question I was hoping you can help me with is, how do you treat gastritis if it is linked to anti-vinculin? The main theory going around seems to be that impaired motility causes food to get trapped in the small intestine, which puts pressure on the stomach which delays stomach emptying and prolongs exposure of acid and food to the stomach lining. If this is the case, what do we do about it?

I have been taking prokinetics(ginger and artichoke pill) and I have been doing exercise and it has been successful in getting me to induce stomach growling 4 hours after waking up, but I'm not entirely sure if it's doing anything to help my stomach heal.

Any input is appreciated.

Posted Aug 21, 2026, 2:33 AM UTC

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