So... what really is the best way to farm berries?

A lot of people talk about the famous Berries 3 and Big Haul 3 (or 2) combo... but I spent literally THREE HOURS trying to get it (and it wasn't even Big Haul 3...)

It got me thinking... how many berries could I have earned during those two hours? So I wanted to know what you guys think: is it better to spend hours getting the perfect combo, or just go for multiple Hyperspace runs? Also, what's better—focusing on Big Haul or Berries? Or maybe not focusing on either, just grabbing any random Donut and doing multiple Hyperspace runs?