MTX Injectible Side Effects

As of April 2026, i had to switch to the injectible methotrexate instead of taking the oral tablets to manage to flares and so far it's bee working.

At first i felt, great, no issues. A couple of weeks in, i started to get anxieties pre-injection. it was a sinking feeling of "oh no i can't believe the weekly injections are my new normal for good" and it just made me always feel anxious before i'd have to suck it up and just do the shot.

i brought that up to my rheuma and he actually told me we can try switching back to the tablets bec he didn't want me to experience anxieties but i decided to just suck it up and power through with the injections because it's working.

i just noticed now, i tend to get side effects after the injection. like i get headaches and i'm more fatigued than usual and it lasts up to 24 hrs. is this normal? that i'm only feeling these effects now months into taking the injection? there have been no changes to the dose, it's just 0.6ml.