nums qs plzz help!!

https://preview.redd.it/1dvreionrwoh1.png?width=823&format=png&auto=webp&s=6707eb19cb6af80502f9932b223ecb959d6f1b36

guys wo enzymes jo wide range of substrates ke sath work kr sakti hain wo regulatory hoti hain ye non regulatory. Lock and key model regulatory hoga ya non regulatory?? like the notes that i have state that lock and key model is non regulatory and those enzymes work with specific substrates. pleasee tell me which opt is right