Trip Report - Beware of IBS and 270mg Mescaline Fumarate

Years ago I ingested a full spectrum cactus tea and had a wonderful lite experience full of empathy for all things. Also had prior experiences with LSD and shrooms. So I was curious to ingest some mescaline fumarate via the CIELO tek. So I prepared mentally over the last few weeks and then set aside a dedicated day with a trip sitter and also set aside a recovery day. Also prepared an instrumental-only playlist. Probably the most prepared I've ever been for a trip and felt really good about it.

I woke up early and my body felt quite rested and my mind in a good headspace. So I first drank a cup of strong ginger tea, ate some breakfast, and then digested a bit. Then I made another cup of ginger tea, let it cool to room temp, added in 270mg of mescaline fumarate, and drank it slowly over the next 30 minutes.

• I felt the mental effects come on slowly along with some nausea, as expected. Around the 2-hour mark the nausea was intense and so I vomited.
• From there until the 5-hour mark I vomited an additional 4 times in total. I had strong closed eye visuals, some euphoria, strange discordant thoughts, and yet no feelings of connectedness or empathy. The strong stomach cramps from vomiting never went away and so it heavily dominated the entire experience for me. At the 12-hour mark I still felt a bit sick to my stomach, although it slowly returned to normal.
• Throughout the experience I constantly felt like I needed to shit, but was constipated due to the severe stomach cramps. Extremely unpleasant to be tripping while overwhelmed by feelings of vomiting and shitting.
• Also my entire body felt very physically weak, which is odd for me being an obsessive rock climber. Looking back at the experience, it's comparable to a time when I was terribly ill some years ago. Really felt like a mild form of poisoning. Definitely a very difficult experience, a physical struggle, and not enjoyable. I got some good things out of it mentally but physically it was terrible.

For my whole life I've lived with moderate to severe IBS as a stomach condition. Normally this just means that I stay away from trigger foods such as heavy cream, fried foods, raw onions/garlic, highly caffeinated drinks, wine tannins, and too much animal fat. So I'm thinking that my stomach cannot easily process the mescaline fumarate specifcally, perhaps related to my IBS. While my mind was ready and active, the physical symptoms dominated and so I suffered while waiting for my body slowly try to digest it.

So I wanted to give a warning to anyone else out there with IBS and considering taking mescaline fumarate. Maybe I'm an edge case, maybe not. Beware!