Trying Trintellix again after year of Spravato?

I tried Trintellix 3 years ago with no success, and then switched to Spravato. The Spravato has been amazing, but I'm about to switch down to maintenance dosing. My psych wants me to add some more traditional anti-depressants to my regimen to offset the lower Spravato dosing.

I've been told that long term use of Spravato is known to rewire pathways in a way that can make previously ineffective medications actually work again.

Has anyone here made the switch from Trintellix, followed by Spravato back to Trintellix?

Thanks for your thoughts!