Does getting staph acne mean staph is in the bloodstream? Immuno-compromised and considering/worried about antibiotics.

Physician Responded

30F, 150lbs, have Crohn’s, on Infliximab.

• I’ve had a recurring staph infection in my ears and nose, and have developed staph acne on my butt, stomach. Ears for 8 months, the rest all in the last 3 months. • 1 round of oral amoxicillin antibiotics didn’t help my ears, and the staph in my nose & body happened after them. • Topical antibiotics on my ears and nose haven’t helped thus far. Nor has doing the decolonizing procedure (chlorhexidine + mupirocin for a week) • I am on an immunosuppressant. • I am worried that staph is in my bloodstream and that topical solutions aren’t enough. • I started taking bacillus subtillus probiotics 2 weeks ago, hoping that would decolonize the gut staph.

So: Does getting the staph acne mean that the staph is in my bloodstream? Which could lead to sepsis? Should I go on antibiotics again? Or could the staph infections in multiple areas be caused by staph in the gut and perhaps the probiotics will suffice?

(I’ve read multiple accounts of people dealing with staph infections for year and doing multiple rounds of antibiotics to no avail, and am worried about doing that while on immunosuppressants, or developing antibiotic resistance.)

Posted Sep 13, 2026, 6:24 AM UTC

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