Is there a different antidepressant that can help with motivation besides Wellbutrin?
Like the title says? Is there something else out there that can help with lack of energy and motivation and brain fog that isn’t Wellbutrin?
300 mg Wellbutrin worked for me for a very long time until I couldn’t tolerate it anymore because it started to cause horrible overstimulation, anxiety and insomnia and other weird side effects I never used to get from it before. And those side effects were severe dizziness making me have poor balance, vertigo, blurry vision, hot flashes, burning sensations all over my body and hands, severe headaches, horrible insomnia and sleep disturbances, facial twitches, muscle stiffness and weakness, cold hands etc. And once those side effects escalated I eventually dropped back the dose to 150 mg. But 150 mg just isn’t working for me at all and gives me no therapeutic benefits whatsoever. 150 mg just makes me wired and tired and only gives me some of the residual overstimulation/anxiety/ horrible panic attacks I had at 300 mg, but much less in intensity.
I also think my body just developed a tolerance to Wellbutrin and it’s just not working for me anymore. I was on it for almost five years. So since Wellbutrin doesn’t work for me anymore, is there a different antidepressant that can help with energy, motivation and brain fog? I do have atypical depression with anxiety features. SSRIS have not worked for me either and essentially gave me no relief at all.
So what other options are out there? I’m honestly starting to give up at this point finding something different. Would like to her all your suggestions if you have some?
Posted Sep 21, 2026, 6:14 PM UTC