What could be the impact of low estrogen and high progesterone receptor expression?

Hi all, could I get some advice please form this subreddit?

So 2-3 years ago, I took progesterone as a male and have felt bad since and didn't know why. Recently, I discovered tofu makes me feel better, and I think it's because of the estrogen. I had been avoiding estrogen raising foods since taking the progesterone, and I think the lowered estrogen + the progesterone I took down regulated my PR expression for a long time. Is PR expression lowering long term possible first, and second, as a male what could happen in my body if this is true? Btw, I am not trans, I simply want some advice from those who might know in detail the effects of estrogen, progesterone, and PR expression changes.

Thank you