Psychs and Antidepressants

So my mom is on a bunch of antidepressants and learned after trying she can’t get high on psychs like shrooms because she doesn’t have receptors available or something? But I don’t have any problem taking psychs and SNRIs, previously SNRIs.

Can anyone explain a little further?

Also re seratonin syndrome & shrooms, plur.

People act like it’s a huge risk factor, but looking for some honest life experience rather than a dare presentation

I have experienced this before, but only because of prescriptions (Wellbutrin & adderall). I immediately discontinued Wellbutrin & never will take it again.