Any ideas for cool 'Cursed' Items in Rebirth?

Just wondering if any of you have any ideas for items in Rebirth that carry a huge benefit at a large cost? I think these items are very interesting, and although there are a few already (9 lives, soy milk etc) I think there could be more.

So, does anyone have any ideas? Either write them as a comment below or link me to ones you've found or posted elsewhere, I'd love to see them :)

Just so you know what I'm talking about, here's a couple I posted: Blue Baby's Curse and Countdown