Setting up new shop - Question about size variations for clothing

So I'm working on setting up my first shop. I'll be selling t-shirts with my own designs on them. I've got just about everything ready to go, now to create the listings. I'm planning on selling all of my designs on men, women, and kids tshirts.

I'm setting up the first listing now and getting my first chance to look through the options. I can list as unisex adult but in variations men and women's size are two variations. Is there a way to combine them? Should I do them as two different variations? How do those of you that sell clothing handle this? List Unisex or do two listings for Men and Women?