Do you remember VG Loong trying to play tank Kha'Zix top and failing? This is probably what he had in mind:

I was curious, so i jumped into a couple normals to test it. I got really surprised by the results. Here are the links:

http://matchhistory.eune.leagueoflegends.com/en/#match-details/EUN1/1429337558/37957238

http://matchhistory.eune.leagueoflegends.com/en/#match-details/EUN1/1429183505/37957238?tab=overview

I didn't say it's a good build, just saw some people talking shit about Loong and his pick, so decided to adress the issue. Still assasin Kha'Zix is better:

http://matchhistory.eune.leagueoflegends.com/en/#match-details/EUN1/1429034249/37957238

I'm not trying to show skill, don't call me out on that one :C