I took 30 mg hydrocodone like an hour and a half before a 2C-B trip once. I don't know if it really did much for the trip itself but it was probably helpful to have been in a great mood going into the trip. I've found with 2C-B my mood going into the trip really doesn't matter though, so it might have been more useful before taking something like LSD.

How's it like? I'm experienced with both separately. I'm thinking of taking a Zofran an hour before I drop the 2C-B to reduce nausea.

I'm thinking low-ish doses for the first time combining, 10-15mg oxy and 15mg 2C-B. However I'm looking for dose suggestions, I do oxy semi regularly but my tolerance isn't that high, a full 30 would get me nodding hard and I don't want to be too out of it to enjoy the 2C-B trip.

What timing is best for this? At the same time or one before the other? What's the safety profile like?

Looking your experiences and advice!

Oxy and 2C-B combination?