Just got laid off notice (45 days) - how long does it normally take to get a new job ?

This is my 2nd job out of college so Ill be looking for a 3rd. I'm about to start applying - I was wondering about how long do you guys think it will take to get a new job that is enjoyable? I'm in Austin,TX with a background in .net but Im looking for a job in Node with 4 years experience making ~110k annually.

They are laying everyone off because the company just lost the contract that paid for me and about 20 other people.