Hi everybody!
I am planning to research MXE very soon, and I was wondering if it would be safe to combine it with Levosulpiride, which I was prescribed to treat dispeptic syndrome.
The point is, Levosulpiride is an antipsychotic and a selective Dopamine D2 receptor antagonist, whereas MXE is a Dopamine D2 receptor agonist.
Would this combination be safe or not?
Thanks in advance :)
Posted Apr 1, 2017, 7:39 AM UTC
You may find yourself immediately in antipsychotic withdrawal which could be bad also on MXE; start slow be responsible etc etc.
What is this MXE you speak of and where might one find it?
It is from a friend's stash, which I think he sourced nearly two years ago.
So there's no recent MXE source to speak of, unfortunately.
I don't see why it would be unsafe. It will negate some of the effects of the MXE though. D2 agonism seems to be important to both ketamine and MXE's pharmacology. I can't say how this would alter the experience though.
It may reduce MXE's manic effects.
I will try this combination out very soon, maybe I could try and combine Levosulpiride with other dissociatives like 3-MeO-PCP, which reportedly doesn't have any dopaminergic activity ( but definetely produces manic effects in users), to see if Levosulpiride would turn the experience to be less "psychotic".
I suspect it to be safe, but the combination would likely modulate the effects of the MXE