Kirk Durston responds to Josh Swamidass on the fraction of random amino acid chains that are functional proteins (see comments)

I remember seeing this a few weeks ago and I had wondered how Durston would respond. He has a more layman-approachable summary on his blog.

thanks for posting this!

Kirk is my friend, but I somewhat sided with Swamidass. I don't think the use of pFam can give the best probability calculations. I gave my take here:

http://theskepticalzone.com/wp/evolution-and-functional-information/comment-page-1/#comment-170939

You can see Swamidass's response to what I said throughout that thread.