r/OrganicChemistry•8 yr. agobackandbuttonTetramethyl Orthosilicate (TMOS) as a Reagent for Direct Amidation of Carboxylic Acidspubs.acs.org/doi/abs/10.1021/acs.orglett.7b03841pubs.acs.orgPosted Feb 7, 2018, 7:19 PM UTC61ShareSave
I'm curious if the proposed mechanism is similar to the mechanism with DCC (carbodiimide) as a reagent for direct amidation. Anyways, I enjoyed reading this way more than I should have. Thanks for sharing!