It works great in Wine on OSX. In fact, for some people the OSX build is broken and Wine is the only option.

Haven't tried it on Linux but I can't see why it would be any different.

The Itch.io Cinco Paus page lists PC support for only Mac and Windows, and I haven't been able to find any notes about it's performance on Linux through Wine. There also isn't a page on the Wine AppDB  - has anyone tried running it through Wine and is able to comment on how well it performs? 

Cinco Paus Wine performance?