[deleted]•

This was made by a group of uneducated poeple most of whom presumably are non medical professionals. It is a good starting point, but there are some serious downsides to it. The "Common Negatives" column is missing a lot of stuff and the doses cannot be trusted. Specifically I take issue with the high doses of huperzine a, caffeine, and melatonin. Taking 1000mcg of huperzine a for a long time will probably fuck you up and leave you much worse off then when you started. 1.5g of caffeine is going to be way too much for a sizable portion of the population. You'll also get a lot of negative side effects by using some of these substances together but that isn't always stated.

If you use it then make sure you verify the information by a few objective and trustworthy sources. This spreadsheet is useful but a work in progress by amateurs and should be treated as such.

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kneb•

this isn't a public document

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darthjure•

This is a great list. I hadn't heard of sulbutiamine - have to do some research on it.

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ntr0p3•

Good stuff, works well, only downside is you can get a tolerance. Like most b-vitamin analogues, it works best if you don't have enough.

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quickfastgoninja•

The doses are incorrect. 12.5 mg/kg is the reported therapeutic dose, with one manufacturer (Arcalion) recommending a ceiling of 600 mg.

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[deleted]•

This document was a collaborative effort made possible by the Immortality institute forum members.

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EallaFome•

this "low daily dose" for Adderall is 5mg. I'm 150lbs and prefer no more than 2.5mg, once daily.

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TheOuts1der•

I find it hilarious that the ones offered only in Russia offer increased tolerance to coldness. All in all, very good starting point. Thank you!

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enigmo•

how many of those listed was sicarius taking when he made this spreadsheet?

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Farrix•

Holy shit. Thanks!

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ntr0p3•

Dear sir, Thank you. :)

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boomerangotan•

New research shows that nicotine is not addictive unless administered with an MAOI. (MAOIs are found in tobacco)

I find this interesting. I've never smoked, but out of curiosity I tried some patches a few years ago and wondered what the deal was, as I experienced no addictive compulsion.

I used 14mg on various days for a few weeks. My observation was that it felt mostly like long-lasting caffeine with decreased social inhibition and a very mild euphoria. I never felt like I had to have one, and I decided to simply stop taking them due to the vasoconstrictive nature of nicotine being contraindicated with my elevated blood pressure.

At the time, I wondered why there was no addictive feeling. This explains it.

Edit: http://www.ncbi.nlm.nih.gov/pubmed/16177026

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unpythonic•

I only have experience with adderall since I have that prescribed for Adult ADD. I take 2 5mg IR tablets a day.

Anyway, I take exception to "IR lasts 4-5 hours." I've been taking this dose (10mg/day) with drug holidays every weekend for 6 weeks now. A 5mg tablet NEVER lasts 5 hours. I generally say that I get 3 good focus hours per tablet with the first two being "really good." I also have to take the dose without food or the effects are substantially muted. Is this something I should bring up with my doctor?

When these were prescribed the doctor said I shouldn't take one after 3PM or it will interfere with my getting to sleep. I know from experience that I can take a 5mg Adderall at 6PM and have no trouble getting to sleep at 11. I've asked the doctor to look into Modafinil (mainly because it is schedule IV and Adderall is schedule II) but I wonder if I metabolize Adderall unusually fast and if so if I should up the dose or be otherwise concerned.

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[deleted]•

Good list. I suppose the next logical step is to include the type of evidence supporting effectiveness. That's what I'd like to see anyway.

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