My guess would be that a well constructed interlocking grid would be strongest, but it would have to be done to reasonably tight tolerances or it could end up being weaker than the other options. 

An aligned grid would probably be next strongest but a little trickier to put together than offset. 

Offset I can’t imagine would be noticeably worse than aligned and easiest to build.

I went with offset on an assembly table I made, worked out really well. It’s all hidden inside anyway when it’s done so I figured just go with the quick reliable option. Maybe if I needed to make another torsion box for some reason I’d go with interlocking just for the satisfaction of it!

I'm looking to build an outfeed/assembly table with a torsion box top. 

Is the alignment style inside a torsion box going to make much difference to the overall strength and rigidity of the box?

Torsion box question: aligned grid or offset grid or interlocking grid?