NBME 17 Question about macrophages

Spoiler

Pt with AIDS that develops pulmonary tuberculosis. No CD40+ T cells. Which cellular components most likely to have deficient function in the tuberculosis lesion in the patient's lung.

a. Eosinophils

b. Fibroblast

c. Langhans giant cells

d. Macrophages

e. Neutrophils

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Answer: D

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I know the whole CD4/ macrophages thing. Why wouldn't it be Langhans giant cells? If macrophages are deficient then obviously langhans are going to be deficient? Am I missing something here?

Posted Jun 4, 2020, 11:48 PM UTC

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