RCT: "Effect of Calcifediol (Vitamin D metabolite) Treatment and best Available Therapy versus best Available Therapy on Intensive Care Unit Admission and Mortality Among Patients Hospitalized for COVID-19: A Pilot Randomized Clinical study"
sciencedirect.com/science/article/pii/S096007...Posted Sep 4, 2020, 3:43 PM UTC
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My Registered Dietitian friend who works for a large hospital system in GA says that D is standard protocol for every COVID person being admitted. She also said that every person admitted had extremely low D levels. Not to make correlation into causation, but it was noticed. In full transparency, I do not recall if it is admitted to general or ICU.
This metabolite is interesting as it allows some of the potential Vitamin D activation bottleknecks to be circumvented in the extremely ill since magnesium status and functional kidneys etc are important to turn the inactive reserve form into the active form.