3080 is a hot potato, move radiator to front mount with some good exhaust fans at top and rear.  Ambient temps inside shouldn’t be an issue and you’ll keep the cpu running cooler in this configuration.

Run some thermal tests on your current config and jot down the figures, then throw the rad in the front and see if there’s a difference. It’ll effect (affect?) the 3080 similarly.

Most people say there isn’t much of an effect as long as your exhaust is good

Nah, my only real concern was whether or not the heat from the radiator would have more of an impact on the gpu, than the heat from the gpu would have on the cpu.

Will having the rad in the front cause clearance issues?

Rtx 3080 and cpu aio radiator placement.