Cytokine elevation in severe and critical COVID-19: a rapid systematic review
thelancet.com/journals/lanres/article/PIIS221...Posted Oct 29, 2020, 7:58 PM UTC
43
Posted Oct 29, 2020, 7:58 PM UTC
I think they had to check IL-1 beta or IL-1 alpha.
TLDR: Although cytokine concentrations are elevated in patients with severe and critical COVID-19, the degree of cytokinaemia is markedly less than that seen in other disorders associated with elevated cytokines [septic shock, ARDS, Cytokine release syndrome]. Given these findings, the descriptor cytokine storm is problematic and alternative mechanisms of COVID-19-induced organ dysfunction are worth considering.
No wonder trials of cytokine inhibitors are failing
[deleted]
[removed]