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dopa05•

I think they had to check IL-1 beta or IL-1 alpha.

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DimdammOP•

TLDR: Although cytokine concentrations are elevated in patients with severe and critical COVID-19, the degree of cytokinaemia is markedly less than that seen in other disorders associated with elevated cytokines [septic shock, ARDS, Cytokine release syndrome]. Given these findings, the descriptor cytokine storm is problematic and alternative mechanisms of COVID-19-induced organ dysfunction are worth considering.

No wonder trials of cytokine inhibitors are failing

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