Technical article: Updated estimates of the prevalence of post-acute symptoms among people with coronavirus (COVID-19) in the UK
ons.gov.uk/peoplepopulationandcommunity/healt...Posted Sep 16, 2021, 2:32 PM UTC
Posted Sep 16, 2021, 2:32 PM UTC
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Prevalence of any symptom at a point in time after infection. Among study participants with COVID-19, 5.0% reported any of 12 common symptoms 12 to 16 weeks after infection; however, prevalence was 3.4% in a control group of participants without a positive test for COVID-19
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Prevalence of continuous symptoms after infection. Among study participants with COVID-19, 3.0% experienced any of 12 common symptoms for a continuous period of at least 12 weeks from infection, compared with 0.5% in the control group
Approach 3: Prevalence of self-reported long COVID.
An estimated 11.7% of study participants with COVID-19 would describe themselves as experiencing long COVID (based on self-classification rather than reporting one of the 12 common symptoms) 12 weeks after infection, and may therefore meet the clinical case definition of post-COVID-19 syndrome, falling to 7.5% when considering long COVID that resulted in limitation to day-to-day activities; these percentages increased to 17.7% and 11.8% respectively when considering only participants who were symptomatic at the acute phase of infection.
Approach 2: Prevalence of continuous symptoms after infection.
Among study participants with COVID-19, 3.0% experienced any of 12 common symptoms for a continuous period of at least 12 weeks from infection, compared with 0.5% in the control group; this estimate of 3.0% is based on a similar approach to the one we published in April 2021 (13.7%), but is substantially lower because of a combination of longer study follow-up time and updated statistical methodology. The corresponding prevalence estimate when considering only participants who were symptomatic at the acute phase of infection was 6.7%.
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