Scared to start Mirt

I've been on antidepressants for about 13 1/2 years now, after living with untreated depression and anxiety through most of my life. I was on Zoloft for about 4 years until it started pooping out on me. I was then on Effexor, Wellbutrin (a nightmare), Effexor again briefly until I started Lexapro. This was good for me for about 4 years, then I started feeling the lack of motivation, constant blahs, sleepiness, and anhedonia. I felt like I was sleepwalking through life without really feeling or fully experiencing anything. My anxiety was also kicking up. My psych added buspar, but thought I should keep the Lexapro. Buspar helped with anxiety, but I still felt flat due to the Lexapro. I finally pushed to get off of Lexapro in January and she recommended Viibryd. I did a slow taper off Lex, onto Viibryd (kept the Buspar). I didn't really notice a tremendous difference in mood while on the lower does of Viibryd, but had vivid, anxiety-producing dreams, bad sleep, and horrible night sweats. When I hit 20mg, my anxiety ramped up to unbearable levels. Literally everything triggered anxiety, anything I read, listened to, watched, people I talked to, etc. I would literally just sit and stare, trying to fight back the anxious thoughts. I felt hopeless and terrified of the future, and suicidal ideation started last weekend, so that was it. I called my psych and told her that this was not for me. She strongly feels that mirtazapine is the right drug for me, but I'm so gun-shy about trying a new drug after Viibryd being a nightmare. I called her the next day and asked to just go back to Lexapro until our appointment next week, and she agreed to call in a 10 day script for 10mg (was on 20mg when went off). I expressed my anxiety about the vivid dreams and weight gain, but she seemed to downplay these as "rare", but we'll discuss further on Thursday. So, I'm currently on 10mg of Lex, 15mg of Buspar a day. Feeling much better than I did early this week while still on Viibryd, but obviously still not great.

So, I guess my question is, has anyone gone from Lexapro to mirtazapine successfully? Other than the sleepiness and perhaps slight weight gain (<5lbs), I didn't suffer much in the way of side effects with Lex. I'm mostly looking for my anxiety and depression to be controlled without feeling drowsy or manic. I feel like with the double-whammy of depression and anxiety I have to choose between my depression being treated, but feeling hyper/manic with bad anxiety, or having my anxiety under control while feeling tired and emotionally flat.

Posted Mar 13, 2022, 4:51 AM UTC

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kyelou75•

I’m on mirtazapine and really like it , no side effects for me other than initially tired in the mornings. Increase appetite just after I take it, I sleep well , currently on 15mg will increase next week to 30mg brung a better dose for anxiety and depression. I’m so sensitive to meds and tried so many, I keep coming back to mirtazapine.

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fuckfcbauerninzest•

did you not feel drugged at all? how about your stomach feeling like it's in slow motion?

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kyelou75•

At first yes a little tired but now I feel good most of the time, anxiety is starting to settle a bit, I couldn’t leave the house . Now I’m leaving the house and doing a bit more for myself. I’m staying on 15mg . My stomach feels fine , I haven’t had my ppi stomach meds in months and I was on them for years. Don’t be afraid of mirtazapine, feel free to msg me anytime. I’m trying to help myself and not just rely on the meds to cure me. Exercise and self care are very important in recovery even if you don’t feel like it. Walk to the letter box and back each day, have a shower ( I know how hard this can be trust me) implement small things at a time and do them daily. Set yourself a routine , it all helps. Insight timer app is fantastic for sleep and anxiety meditations, I just listen and zone out.

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winsomeyoldster•

I take 20mg Lexapro, 300 mg gabapentin and 30mg mirtazapine and have no problems. I have been talking the mirtazapine for about six years.

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tvymola•

I take 30mg of Mirtazapine and I love it. I sleep like a baby! The grogginess the next day wanes after a week or two. Don't be afraid to start it. It will help you tremendously.

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Alone-Show-6791•

What about a hyper manic med with low dose lithium? Stops the suicidal ideation and low doses are pretty chill. I think I felt a bit dumb at 300 a day.

1

Most of the things your expressing are common side effects of antidepressants when starting and dose increases. When you increase your dose everything starts over. It can take a couple of weeks for side effects to go away. 4-6 weeks to see full improvements…. 8 weeks for some people…. Also, when you tapped off of a medication you can have side effects. I would recommend adding an anxiety medication while starting or upping a dose on an antidepressant. There is Hydroxyzine(might make you sleepy when first starting it), Propranolol, Gabapentin, or Buspar. Natural Options that help: L-theanine, Omega 3, Ionic Magnesium, Tart Cherry, Lemon Balm, Zinc, Vitamin B1, and Passion Flower.

Also, Doses up to 15 are used for sleep. 30mg for Depression. It will make you hungry so expect weight gain. It gave my husband restless legs, impulsesness, mood swings, tossing and turning and headaches. He is also bipolar tho.

I would recommend Trillinex, Cymbalta, Luvox, Pristiq, or amitriptyline with something like Depakote or Olazapine(low dose).

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GingerHalOP•

Thanks for everyone's input and sharing your experiences! After taking a couple of days and talking it through with my husband, I decided to start the mirtazapine tonight. I'll never know if I don't try, and I'm seeing my psych in 4 days for follow up either way. Even if this doesn't work out for me and I need to switch again, I'm making forward progress; going back to Lexapro is just doggy paddling to keep my head above water. That's exhausting and getting me nowhere fast.

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[deleted]•

[deleted]

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Eduard220•

Mind giving us an update op?

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GingerHalOP•

Sure! I'm 7 doses of 15mg in, and I'm definitely doing better than I was a week ago. Suicide ideations are gone, anxiety is more manageable, and I feel like I'm able to focus on my day to day without being overwhelmed. I'm still experiencing bouts of sadness, hopelessness, and anxiety, but they're fewer and farther in between. My main side effect is sleepiness, especially when I wake up in the morning (I take it about an hour before going to bed, I get roughly 8 hours a night). It's been gradually getting better, though. There is some increase in appetite, but I'm not constantly eating. I saw my psych on Thursday, and she plans to keep me on 15mg until our next appt next month, then we'll talk about an increase. I'm feeling hopeful about it for sure!

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Eduard220•

Glad to hear it helped you too, I ve been on 30mg mirt, 5mg lexapro and 0.5 alprazolam for about 3 weeks and I def feel better, started first few days at 15mg, then upped to 30, by week 2-3 the side effects fade away. Anyway a dose în the lower range like 15mg makes you more sleepy and groggy ive seen, whereas on 30mg now I feel refreshed în the morning and do some things I have to do, feel productive.

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GingerHalOP•

That's great to hear! The plan is to move me up to 30mg, but I'm just taking it slow as I'm coming down from the Viibryd 20mg and adjusting to the mirtazapine. I do feel slight improvements each day, so I feel like I'm on the right track with this med.

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