Adam and Eve debating

I was debating with my mom, explaining that it's ridiculous to think that two people could have populated the entire earth, to which she said well amino acids couldn't have formed into humans (I was explaining abiogenesis to her) and she told me that tribes in Africa inbreed closely all the time and they still aren't dead (from recessive disorders like heart disease, etc.). What do I say to that and what are some good Adam and eve arguments?