Seizure Risk (Wellbutrin+DXM+Kratom)
It is my understanding that wellbutrin potentiates DXM and does not normally have a risk for serotinin syndrome when taken with DXM. I also understand that wellbutrin alone can increase risk of seizures.
My gf who is a part of this community (won't share her name for her privacy. She is okay with me making this post as a warning for others) had a few seizures tonight. Her weight is 105lbs, dose was 600mg robotabs (freebase). She takes 150mg Wellbutrin 2x a day, and 3-6g of kratom daily. She never had seizures before. Last night 1hr after coming up she had a few seizures according to her mom (nurse).
TL;DR: be careful what you mix DXM with. There isn't much information about kratom and DXM but kratom does seem to have affinity to serotinin receptors (Source: https://pubs.acs.org/doi/10.1021/acs.jmedchem.1c00726 ) Kratom combined with wellbutrin and DXM seems to be dangerous.
Do you guys have any experiences with regular kratom use and DXM tripping together? I'm mainly interested in people who use kratom daily but one off users are welcome to post too.
Posted Oct 25, 2022, 3:58 AM UTC
Hey thanks for posting. I'm a fairly frequent kratom user, ~3 times a week. Ocassionally I indulge in some robotabs as well.
I haven't done heavy research into the combo, but I think seizures are a possible side effect of higher dose of dxm too. I'm not sure if kratom has any potential to increase risk or not.
What I can say, from personal use. Is that a lot of times I'll take a medium size dose of kratom ~ while on my robotabs to counteract any diarrhea. They seem to be synergistic and I definitely wouldn't be concerned with medicinal doses. I like the combo and it seems to bring me increased euphoria. I would be more suspect of the dxm than the kratom.
Yeah especially with the weight of her and the use of Wellbutrin too.
kratom has been proven to not cause seizures, but to lower the seizure threshold.